Painting, commissioned by Emperor Charles V, was performed in Augsburg in 1548. Isabella of Portugal married Emperor Charles V in 1526. She died very young when she was only 36 years old, and long before Charles V authorized Titian to paint her portrait. Her pale face emphasizes her softness, which is also visible in the thin fingers of her hands.
The whole portrait is centered around the excellent color harmony of red, white and gold. A charming color contrast is provided by the blue and green shades of the landscape.
Related Paintings 
Portrait d’Isabelle de Portugal – Titian Vecellio 
Mourning mother by Titian Vecellio 
The Trinity in Glory by Titian Vecellio 
Portrait of a Girl by Titian Vecellio 
Portrait of Paul III by Titian Vecellio 
Portrait of Cardinal Ippolito de Medici by Titian Vecellio 
Portrait of the daughter of Titian Lavinia by Titian Vecellio 
Retrato de Isabel de Portugal – Tiziano Vecellio
Portrait d’Isabelle de Portugal – Titian Vecellio Mourning mother by Titian Vecellio The Trinity in Glory by Titian Vecellio Portrait of a Girl by Titian Vecellio Portrait of Paul III by Titian Vecellio Portrait of Cardinal Ippolito de Medici by Titian Vecellio Portrait of the daughter of Titian Lavinia by Titian Vecellio Retrato de Isabel de Portugal – Tiziano Vecellio