The long wooden panels that covered the space under the altar picture often became a stumbling block for artists. Usually they were filled with multi-figure scenes from the lives of saints, but Botticelli preferred simple compositions based on a certain event.
In this case, the event is the extraction of the heart of St. Ignatius, probably Ignatius of Antioch, an elderly man who ended his days a martyr in Rome, where he was thrown to the lions to be torn. The painting was written, like the Vision of St. Augustine, for the altar of the church of San Barnaba.
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